NSC59984
NSC59984通过MDM2和泛素-蛋白酶体途径而诱导突变型p53蛋白降解。NSC59984作用于大多数肿瘤细胞的EC50值显著低于正常细胞, 作用于P53--null HCT116细胞的EC50为8.38 μM。
CONCANAVALIN A (TYPE VI) -AGAROSE
PEP, POST TRANSLATIONAL MODS, GLYCOSYLATION, PURIFICATION LECTIN AFFINITY RESINS
L-GLUTAMINE-AGAROSE
PEP, CHROMATOGRAPHY, AFFINITY RESINS, AMINO ACIDS
ADIPIC ACID DIHYDRAZIDE-AGAROSE
PEP, CHROMATOGRAPHY, AFFINITY RESINS, HIGH VOLUME
ADIPIC ACID DIHYDRAZIDE-AGAROSE
PEP, CHROMATOGRAPHY, AFFINITY RESINS, HIGH VOLUME
IMINODIACETIC ACID-AGAROSE ATTACHED*EPOX Y-ACTIVATED
PEP, CHROMATOGRAPHY, AFFINITY RESINS, IMAC
PROTEIN A-AGAROSE
PEP, CHROMATOGRAPHY, AFFINITY RESINS, PROTEIN A
REACTIVE BROWN 10-AGAROSE
PEP, CHROMATOGRAPHY, AFFINITY RESINS, DYES