MMP8 (Human) ELISA Kit
产品名称： MMP8 (Human) ELISA Kit
英文名称： MMP8 (Human) ELISA Kit
产品编号： KA0396
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- MMP8 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human MMP8.
- Calibration Range:
- 156 to 10000 pg/mL
- Limit of Detection:
- 10 pg/mL
- Reactivity:
- Human
- Storage Instruction:
- Store the kit at 4°C for 4 months. For long term storage, please store at -20°C for 8 months.
- Quality Control Testing:
- Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
- Protocol:
Protocol Download
- MSDS:
- Download
- Suitable Sample:
- Body Fluid, Cell Culture Supernatant, Plasma, Serum, Tissue Lysate
- Sample Volume:
- 100 uL
- Label:
- Biotin-conjugate
- Detection Method:
- Colorimetric
- Regulation Status:
- For research use only (RUO)
- Publication Reference
- 1.
- Functionally significant SNP MMP8 promoter haplotypes and preterm premature rupture of membranes (PPROM).
Wang H, Parry S, Macones G, Sammel MD, Ferrand PE, Kuivaniemi H, Tromp G, Halder I, Shriver MD, Romero R, Strauss JF 3rd.Hum Mol Genet. 2004 Nov 1;13(21):2659-69. Epub 2004 Sep 14.
- 2.
- Structure and expression of the cDNA encoding human neutrophil collagenase.
Devarajan P, Mookhtiar K, Van Wart H, Berliner N.Blood. 1991 Jun 15;77(12):2731-8.
- 3.
- Human neutrophil collagenase. A distinct gene product with homology to other matrix metalloproteinases.
Hasty KA, Pourmotabbed TF, Goldberg GI, Thompson JP, Spinella DG, Stevens RM, Mainardi CL.J Biol Chem. 1990 Jul 15;265(20):11421-4.
- Application Image
- Quantification
- Entrez GeneID:
- 4317
- Gene Name:
- MMP8
- Gene Alias:
- CLG1,HNC,PMNL-CL
- Gene Description:
- matrix metallopeptidase 8 (neutrophil collagenase)
- Omim ID:
- 120355
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq
- Other Designations:
- PMNL collagenase,matrix metalloproteinase 8,matrix metalloproteinase 8 (neutrophil collagenase),neutrophil collagenase
- Related Disease
- Breast cancer
- Breast Neoplasms
- Bronchiectasis
- Carcinoma, Basal Cell
- Carcinoma, Hepatocellular
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Chorioamnionitis
- Connective Tissue Diseases
- Coronary Artery Disease
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Fetal Diseases
- Fetal Membranes, Premature Rupture
- Genetic Predisposition to Disease
- Hepatitis C, Chronic
- Infection
- Inflammation