FASTK,Fas活化的丝/苏氨酸激酶抗体

产品编号HZ-1765R
英文名称FASTK
中文名称Fas活化的丝/苏氨酸激酶抗体
别 名FASTK; Fas-activated serine/threonine kinase; Fas activated serine threonine kinase; Fas activated serine threonine kinase isoform 1; Fas activated serine threonine kinase isoform 4; FAST; FAST kinase; FLJ13079.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学 信号转导 细胞凋亡 激酶和磷酸酶
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat,
FASTK,Fas活化的丝/苏氨酸激酶抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量60kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human FAST kinase
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
FASTK,Fas活化的丝/苏氨酸激酶抗体PubMedPubMed
产品介绍background:
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis promoting nuclear RNA binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full length natures have not yet been determined.

Subunit:
Interacts with TIA-1 and TIAR.

Tissue Specificity:
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Similarity:
Belongs to the FAST protein kinase family.
Contains 1 RAP domain.

Gene ID:
10922

FASTK,Fas活化的丝/苏氨酸激酶抗体Database links:
Entrez Gene: 10922 Human
Entrez Gene: 66587 Mouse
Entrez Gene: 296741 Rat
Omim: 606965 Human
SwissProt: Q14296 Human
SwissProt: Q9JIX9 Mouse
Unigene: 647094 Human
Unigene: 28123 Mous

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.