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Mouse CTSZ / CTSX / Cathepsin-Z Antibody Datasheet
 
 
 
 
 
 
 
 
 
Order or Inquire for CTSZ Antibody product
 
 
 
 
 
 
 
CTSZ / CTSX / Cathepsin-Z抗体产品信息
 
 
 
 
免疫原 : 
 
 
Recombinant mouse CTSZ protein ( Catalog#50089-M08H )
 
 
 
 
抗体类型: 
 
Rabbit Polyclonal Antibody ( Antibody Purification Platform )
 
 
 
抗体宿主 :
 
 
Rabbit IgG
 
 
 
 
缓冲液 :
 
0.2 μm filtered solution in PBS with 5% trehalose
 
 
 
制备方法 : 
 
 
Produced in rabbits immunized with purified, human cell-derived, recombinant mouse CTSZ ( rM CTSZ ; Catalog#50089-M08H ; NP_071720.1; Met 1 - Val 306 ). Total IgG was purified by Protein A affinity chromatography.
 
 
 
 
 
CTSZ / CTSX / Cathepsin-Z抗体使用指南
 
 
 
 
 
特异性 : 
 
 
 
Mouse CTSZ / CTSX / Cathepsin-Z
 
 
 
 
Western blot : 
 
This antibody can be used at 1 - 2 μg/mL with the appropriate secondary reagents to detect mouse CTSZ  in WB.
 
 
 
储存方法 :
 
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
 Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
 
 
 
 
CTSZ / CTSX / Cathepsin-Z Antibody Related Products & Topics
 
 
相关研究领域:
 
Enzyme>>Protease & Regulator>>Cysteine Protease & Regulator>>Cathepsin Family>>Cathepsin Z/Cathepsin X
 
Cancer>>Angiogenesis>>Cathepsin Family>>Cathepsin Z/Cathepsin X
 
Immunology>>Innate Immunity>>Lysosomal Enzyme>>Cathepsin Family>>Cathepsin Z/Cathepsin X
 
蛋白:
 
 
 
 
Molecule
 
Species
 
Description //For Detailed Info.------CLICK!
 
Cat No
 
 
 
Cathepsin Z/Cathepsin X
 
Mouse
 
Cathepsin Z/Cathepsin X  Protein, Recombinant
 
50089-M08H
 
 
 
 
抗体:
 
 
 
 
Molecule
 
Application
 
Description //For Detailed Info.------CLICK!
 
Cat No
 
 
 
Mouse 
 Cathepsin Z/Cathepsin X
 
WB, ELISA
 
Rabbit Polyclonal Antibody
 
50089-RP01
 
 
 
Mouse 
 Cathepsin Z/Cathepsin X
 
WB, ELISA
 
Rabbit Polyclonal Antibody (Antigen Affinity Purified)
 
50089-RP02
 
 
 
 
 
 CTSZ / CTSX / Cathepsin-Z抗体背景综述
 
 
Cathepsin Z , also known as cathepsin X or CATX, belongs to the C1 family of lysosomal cysteine proteases. Its gene structure and activity properties show several unique features that distinguish it clearly from other human cysteine proteases. It has a very short pro-region that shows no similarity to those of other cathepsins and a three-residue insertion motif that forms a characteristic ‘mini loop’.Cathepsin Z exhibits mono- and di-peptidase activity at its C-terminus, and in contrast to cathepsin B, it does not act as an endopeptidase. It is restricted to the cells of theimmune system, predominantly monocytes, macrophages and dendritic cells. Furthermore, higher levels of cathepsin Z are also found in tumour and immune cells of prostate and gastric carcinomas and inmacrophages of gastric mucosa, especially after infection by Helicobacter pylori.
 
 
参考文献
 
 
 
Santamaría, I. et al., 1998, J. Biol. Chem. 273 (27): 16816-16823.
 
Zala, J. et al., 2008, Journal of Cell Science. 121(16) 2652-2661.
 
 
 
 
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