FITC标记的RFTN2蛋白抗体
产品名称： FITC标记的RFTN2蛋白抗体
英文名称： Anti-RFTN2/FITC
产品编号： HZ-8500R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-RFTN2/FITC Conjugated antibody
FITC标记的RFTN2蛋白抗体
| 产品编号 | bs-8500R-FITC |
| 英文名称 | Anti-RFTN2/FITC |
| 中文名称 | FITC标记的RFTN2蛋白抗体 |
| 别 名 | Raft-linking protein 2; Raftlin-2; Rftn2; RFTN2_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Horse, Rabbit, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 56kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RFTN2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈. |
| 产品介绍 | background: Membrane microdomains known as lipid rafts are implicated in B-cell activation during B-cell receptor (BCR) signal initiation. Raftlin-2, also designated RFTN2 (raftlin family member 2) or raft-linking protein 2, is a 501 amino acid cell membrane protein that is essential for raft cell assembly and maintenance. A lipid anchor protein, Raftlin-2 belongs to the raftlin family and is encoded by a gene that maps to human chromosome 2q33.1 and mouse chromosome 1 C1.2. Human chromosome 2 is the second largest human chromosome, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome is due to mutations in the ALMS1 gene. Subcellular Location: Cell membrane; Lipid-anchor (By similarity). Similarity: Belongs to the raftlin family. Database links: UniProtKB/Swiss-Prot: Q52LD8.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
被称为脂筏的膜微区与B细胞受体（BCR）信号启动过程中的B细胞活化有关。RAFTIL-2，也被指定为rTNT2（RAFTLIN家族成员2）或RAFT连接蛋白2，是501种氨基酸细胞膜蛋白，对于RAFT细胞组装和维护是必不可少的。脂质锚蛋白RaftLIN属于raftlin家族，其编码基因为人类染色体2q33.1和小鼠染色体1 C1.2。人类第2号染色体是第二大人类染色体，由2亿3700万个碱基组成，编码超过1400个基因，约占人类基因组的8%。许多遗传疾病与2号染色体上的基因有关。丑角鳞癣，一种罕见的病态皮肤畸形，与ABCA12基因突变有关。脂类代谢紊乱是与ABCG5和ABCG8相关的。ALSTR综合征是一种极为罕见的隐性遗传性疾病，其原因在于ALMS1基因的突变。