SUMO2/SUMO3 (Center) Peptide
产品名称: SUMO2/SUMO3 (Center) Peptide
英文名称: SUMO2/SUMO3 (Center) Peptide
产品编号: P0287
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of SUMO2/3.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to internal region of human SUMO2/3.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA,Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
- 2.
- SMT3A, a human homologue of the S. cerevisiae SMT3 gene, maps to chromosome 21qter and defines a novel gene family.
Lapenta V, Chiurazzi P, van der Spek P, Pizzuti A, Hanaoka F, Brahe C.Genomics. 1997 Mar 1;40(2):362-6.
- 3.
- Cloning and expression of human homolog HSMT3 to yeast SMT3 suppressor of MIF2 mutations in a centromere protein gene.
Mannen H, Tseng HM, Cho CL, Li SS.Biochem Biophys Res Commun. 1996 May 6;222(1):178-80.
- Entrez GeneID:
- 6612
- Protein Accession#:
- P55854 (Gene ID : 6612);P61956 (Gene ID : 6613)
- Gene Name:
- SUMO3
- Gene Alias:
- SMT3A,SMT3H1,SUMO-3
- Gene Description:
- SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)
- Omim ID:
- 602231
- Gene Ontology:
- Hyperlink
- Gene Summary:
- SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability (Su and Li, 2002 [PubMed 12383504]).[supplied by OMIM
- Other Designations:
- OTTHUMP00000115275,SMT3 suppressor of mif two 3 homolog 1,small ubiquitin-like modifier protein 3
- Entrez GeneID:
- 6613
- Protein Accession#:
- P55854 (Gene ID : 6612);P61956 (Gene ID : 6613)
- Gene Name:
- SUMO2
- Gene Alias:
- HSMT3,MGC117191,SMT3B,SMT3H2
- Gene Description:
- SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
- Omim ID:
- 603042
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
- Other Designations:
- SMT3 suppressor of mif two 3 homolog 2,sentrin 2,small ubiquitin-like modifier 2, isoform a