TBL1XR1 monoclonal antibody (M01), clone 3G7
产品名称： TBL1XR1 monoclonal antibody (M01), clone 3G7
英文名称： TBL1XR1 monoclonal antibody (M01), clone 3G7
产品编号： H00079718-M01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant TBL1XR1.
- Immunogen:
- TBL1XR1 (NP_071347, 81 a.a. ~ 178 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- LSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAASQQGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWN
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.52 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- The repressing function of the oncoprotein BCL-3 requires CtBP while its polyubiquitination and degradation involve the E3 ligase TBLR1.
Keutgens A, Shostak K, Close P, Zhang X, Hennuy B, Aussems M, Chapelle JP, Viatour P, Gothot A, Fillet M, Chariot A.Mol Cell Biol. 2010 Jun 14. [Epub ahead of print]
- Applications
- Western Blot (Cell lysate)
- TBL1XR1 monoclonal antibody (M01), clone 3G7 Western Blot analysis of TBL1XR1 expression in HeLa ( Cat # L013V1 ).
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to TBL1XR1 on formalin-fixed paraffin-embedded human cerebral cortex. [antibody concentration 3 ug/ml]
- Protocol Download
- Immunofluorescence
enlarge this image- Immunofluorescence of monoclonal antibody to TBL1XR1 on HeLa cell. [antibody concentration 10 ug/ml]
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged TBL1XR1 is 0.03 ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 79718
- GeneBank Accession#:
- NM_024665
- Protein Accession#:
- NP_071347
- Gene Name:
- TBL1XR1
- Gene Alias:
- C21,DC42,FLJ12894,IRA1,TBLR1
- Gene Description:
- transducin (beta)-like 1 X-linked receptor 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. [provided by RefSeq
- Other Designations:
- TBL1-related protein 1,nuclear receptor co-repressor/HDAC3 complex subunit
- Gene Pathway
- Related Disease