FOS (phospho T232) Peptide
产品名称： FOS (phospho T232) Peptide
英文名称： FOS (phospho T232) Peptide
产品编号： P1467
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of FOS.
- Immunogen:
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T232 of human FOS.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Dot Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Helicobacter pylori infection activates FOS and stress-response genes and alters expression of genes in gastric cancer-specific loci.
Myllykangas S, Monni O, Nagy B, Rautelin H, Knuutila S.Genes Chromosomes Cancer. 2004 Aug;40(4):334-41.
- 2.
- Tobacco smoke control of mucin production in lung cells requires oxygen radicals AP-1 and JNK.
Gensch E, Gallup M, Sucher A, Li D, Gebremichael A, Lemjabbar H, Mengistab A, Dasari V, Hotchkiss J, Harkema J, Basbaum C.J Biol Chem. 2004 Sep 10;279(37):39085-93. Epub 2004 Jul 15.
- 3.
- Expression of Egr-1, c-fos and cyclin D1 in esophageal cancer and its precursors: An immunohistochemical and in situ hybridization study.
Wu MY, Zhuang CX, Yang HX, Liang YR.World J Gastroenterol. 2004 Feb 15;10(4):476-80.
- Applications
- Dot Blot (Peptide)
- Dot blot analysis of FOS (phospho T232) polyclonal antibody (Cat # PAB0475) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentration was 0.5 ug/mL. P-Pab : phospho-antibody; P-Peptide : phospho-peptide; NP-Peptide : non-phospho-peptide.
- Entrez GeneID:
- 2353
- Protein Accession#:
- NP_005243;P01100
- Gene Name:
- FOS
- Gene Alias:
- AP-1,C-FOS
- Gene Description:
- v-fos FBJ murine osteosarcoma viral oncogene homolog
- Omim ID:
- 164810
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq
- Other Designations:
- FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS),activator protein 1,cellular oncogene c-fos
- Related Disease
- Anorexia Nervosa
- Asthma
- Asthma
- Bronchiolitis, Viral
- Bulimia
- Cardiovascular Diseases
- Diabetes Mellitus, Type 2
- Disease Models, Animal
- Edema
- Genetic Predisposition to Disease
- Infant, Premature, Diseases
- Kidney Failure, Chronic
- Lung Neoplasms
- Osteoporosis
- Ovarian Neoplasms
- Pulmonary Disease, Chronic Obstructive
- Respiratory Syncytial Virus Infections
- Urinary Bladder Neoplasms
- Werner syndrome